转移是恶性肿瘤的主要特征之一,其间涉及多种机制,包括癌细胞离开原有部位,通过血管和淋巴管浸润,在内皮细胞和基质中滞留,诱导新的血管形成,逃避机体的肿瘤免疫监视而形成新的转移灶。大量研究表明,某些蛋白在肿瘤的转移过程中起着重要的作用,其中转移相关基因1(metastasis associated gene 1,MTA1)是近年来发现的与肿瘤发生、 Metastasis is one of the main features of malignant tumors, which involves a variety of mechanisms, including cancer cells from the original site, through the blood vessels and lymphatic invasion, retention in endothelial cells and stroma, induce new blood vessel formation, escape the body’s tumor immunity Surveillance and the formation of a new metastasis. Numerous studies have shown that some proteins play an important role in tumor metastasis, in which metastasis associated gene 1 (MTA1) is found in recent years with tumorigenesis,