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印度的研究人员发现,将不溶于水的匙羹藤酸类化合物制成纳米晶体可增加药物的肠道吸收。研究表明,制药行业生产的半数药物仅能微溶于水。如果口服给药,这些药物将不能产生疗效。使用水溶性“载体”,如环状环糊精,将药物与带电粒子偶联以增加生物利用度是近年来常用的方法。但更
Indian researchers found that adding water-insoluble gymnemic acid compounds into nanocrystals increases intestinal absorption of the drug. Research shows that half the drugs produced by the pharmaceutical industry are only slightly soluble in water. If given orally, these drugs will not work. The use of water-soluble “carriers”, such as cyclodextrins, to couple drugs to charged particles for increased bioavailability is a commonly used method in recent years. But more