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目的探讨心包内置管引流并注入化疗药物DDP配合全身静脉化疗治疗恶性心包积液的疗效、安全性及可操作性。方法对20例恶性心包积液患者经皮穿刺将中心静脉导管置入心包腔,尽可能排尽积液后注入化疗药物。结果20例中4例完全缓解,8例部分缓解。结论B超引导下经皮心包腔内置管化疗,损伤小,安全性好。静脉化疗联合心包腔内化疗疗效好,可明显地控制患者的症状,较单纯静脉化疗能提高疗效,值得在临床推广应用。
Objective To investigate the curative effect, safety and maneuverability of pericardial drainage and infusion of chemotherapy drug DDP combined with systemic intravenous chemotherapy for malignant pericardial effusion. Methods Percutaneous puncture of 20 cases of malignant pericardial effusion placed the central venous catheter into the pericardial cavity, and drained chemotherapy solution as much as possible. Results of 20 cases, 4 patients completely relieved, 8 patients partially relieved. Conclusion B-guided transcatheter percutaneous transluminal catheter chemotherapy, less damage, good safety. Intravenous chemotherapy combined with pericardial chemotherapy is effective, can significantly control the patient’s symptoms, compared with simple intravenous chemotherapy can improve the efficacy, it is worth in the clinical application.