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Dear Editor,Telomeres are specific protein-DNA complexes that protect the ends of eukaryotic chromosomes from fusion and degradation and are maintained by a spe
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Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul 1
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Dear Editor,Telomeres are specific protein-DNA complexes that protect the ends of eukaryotic chromosomes from fusion and degradation and are maintained by a specialized mechanism exerted by telomerase and telomere-binding proteins.Mammalian telomeres contain TTAGGG and are associated with a six-protein (e.g.TRF1,TRF2,TIN2,RAP1,POT1,and TPP1) complex called shelterin (de Lange,2005),which was involved in telomere homeostasis.Similarly to mammalian telomeres,telomeres in most plants are maintained by telomerase and telomere-associated proteins (e.g.AtTBP1,AtTRP1,AtTRB1,POT1,POT2,KU70,and KU80) and consist of tandem arrays of TTTAGGG.
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