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5. Epac2-deficiency leads to more severe retinal swelling, glial reactivity and oxidative stress in tra

Epac2-deficiency leads to more severe retinal swelling, glial reactivity and oxidative stress in tra

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：jinke1983

【摘 要】

：

Ischemia occurs in diabetic retinopathy with neuronal loss, edema, glial cell reactivity and oxidative stress. Epacs, consisting of Epac1 and Epac2, are c AMP m

【作 者】

：

LIU Jin YEUNG Patrick Ka Kit C 

【机 构】

：

DepartmentofAnatomy,DepartmentofOphthalmology,ResearchCentreofHeart,DivisionofScienceandTechnology,S

【出 处】

：

中国科学：生命科学英文版

【发表日期】

：

2015年6期

【关键词】

：

视网膜神经节细胞 缺血/再灌注损伤 氧化应激 神经胶质 细胞反应 缺乏症 闭塞 病变 Epac  retina  ischemia  retinopathy 

【基金项目】

：

supported by the Research Grants Council of Hong Kong(RGC)HKU 764008M to Sookja Kim Chung

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论文部分内容阅读

Ischemia occurs in diabetic retinopathy with neuronal loss, edema, glial cell reactivity and oxidative stress. Epacs, consisting of Epac1 and Epac2, are c AMP mediators playing important roles in maintenance of endothelial barrier and neuronal functions.

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