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间质性膀胱炎(interstitial cystitis,IC)好发生于30～70岁女性,平均43岁,美国妇女的发病率为197/10万,而男性发病率为41/10万。国内尚无明确的流行病学统计资料。间质性膀胱炎严重影响着患者的生活质量,其发病率高,但发病原因和发病机理至今仍未明确。近年来,随着国内外学者对肉毒素进行深入和广泛的研究,提出了A型肉毒素在间质性膀胱炎的新疗法。本文就A型肉毒素在间质性膀胱炎治疗中的研究进展进行综述,临床医师实际工作中参考应用。
Interstitial cystitis (IC) occurred in women aged 30-70 years with an average of 43 years. The incidence of interstitial cystitis in American women was 197 / 100,000, while the incidence in men was 41 / 100,000. There is no clear epidemiological statistics in China. Interstitial cystitis seriously affects the quality of life of patients with high incidence, but the etiology and pathogenesis is still not yet clear. In recent years, with domestic and foreign scholars on botulinum toxins in-depth and extensive research, put forward the A-type botulinum toxin in interstitial cystitis new therapy. This article summarizes the progress of the research on A type botulinum toxin in the treatment of interstitial cystitis, which is used by clinicians in practical work.