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在临床航空医学中，飞行员心电图ＳＴ－Ｔ改变并不少见，但出现Ｔ波巨型倒置的不多，我院对３名飞行员心电图Ｔ波巨型倒置，最后诊断为心尖部肥厚型心肌病，进行了９～２４年长期飞行观察。病历特点：均为男性，飞行时间８００～３５００ｈ，发病时年龄３３～３５岁，无任何症状及体征，心电图胸前导联Ｔ波倒置，超声心动图心尖部心肌不对称性肥厚，运动负荷心电图正常，心肌灌注扫描正常。讨论：心尖部肥厚型心肌病是肥厚型心肌病的一种亚型，以心尖部心肌不对称性肥厚为特征。心电图改变常见巨大倒置Ｔ波，Ｑ－Ｔ间期延长，超声心动图、核磁共振检查可见心尖部不对称肥厚，左室造影可呈“铲型”心。我们报导的这３例飞行员具有心尖部肥厚型心肌病典型心电图、超声心动图特征，虽然在观察中发现心电图Ｔ波倒置深度逐渐加重，为０．３ｍＶ～１．４ｍＶ，超声心动图心肌肥厚逐渐加重，但这种变化进展是十分缓慢的。两名飞行员安全飞行２０年的事实，说明心肌肥厚与该类病人的临床表现及临床过程之间无明显的相关性。因此我们认为：心尖部肥厚型心肌病是相对良性疾病，病程进展缓慢，预后良好，只要病情稳定，无心功能减退，无心电图不稳定的，在严格监控下可限制飞行，但病人必须每年经心脏专科医师及有?
In clinical aviation medicine, pilot electrocardiogram ST-T changes are not uncommon, but the emergence of T-wave giant inversion is not much, our hospital on the three pilots ECG T wave giant inversion, the final diagnosis of apical hypertrophic cardiomyopathy was carried out 9 to 24 years long-term flight observation. Medical history features: all men, flight time 800 ~ 3500h, the age of onset of 33 to 35 years old, without any symptoms and signs, ECG chest T-wave inversion, echocardiographic apex myocardial asymmetry hypertrophy, exercise load electrocardiogram Normal, myocardial perfusion scan normal. Discussion: Apical hypertrophic cardiomyopathy is a subtype of hypertrophic cardiomyopathy characterized by apical myocardial asymmetry. ECG changes common huge inverted T wave, Q-T interval prolongation, echocardiography, MRI showed apical asymmetric hypertrophy, left ventricular angiography can be “shovel-shaped” heart. We reported three pilots with apical hypertrophic cardiomyopathy typical ECG, echocardiographic features, although found in the observation of ECG T wave inversion depth gradually aggravated, 0.3mV ~ 1.4mV, echocardiographic myocardial hypertrophy gradually Aggravate, but progress of this kind of change is very slow. The fact that two pilots flew safely for 20 years shows that there is no obvious correlation between cardiac hypertrophy and the clinical presentation and clinical course of this type of patient. Therefore, we believe: apical hypertrophic cardiomyopathy is a relatively benign disease, the course of slow progression, the prognosis is good, as long as the stable condition, no cardiac dysfunction, no ECG instability, under strict monitoring can limit the flight, but the patient must be a heart Specialist and there?