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目的探讨心律失常应用辛伐他汀治疗的效果及临床价值。方法 80例心律失常患者,随机分为对照组和观察组,每组40例。对照组采用美托洛尔治疗,观察组在对照组治疗基础上加用辛伐他汀治疗,对两组患者效果展开对比。结果观察组治疗总有效率(82.5%)明显高于对照组(55.0%)(P<0.05)。治疗后观察组房性期前收缩为(1142±112)次,室性期前收缩为(1519±123)次,对照组分别为(1932±168)、(2872±142)次,比较差异有统计学意义(P<0.05)。观察组不良反应发生率(12.5%)明显低于对照组(30.0%)(P<0.05)。结论对临床收治的心律失常患者应用辛伐他汀治疗,可显著提高临床治疗效果,改善临床症状,且具较高安全性,有广泛推广应用价值。
Objective To investigate the effect and clinical value of simvastatin in the treatment of arrhythmia. Methods Eighty patients with arrhythmia were randomly divided into control group and observation group, 40 cases in each group. The control group was treated with metoprolol. The observation group was treated with simvastatin on the basis of the control group, and the effect of the two groups was compared. Results The total effective rate (82.5%) in the observation group was significantly higher than that in the control group (55.0%) (P <0.05). After treatment, the atrial contractions were (1142 ± 112) in the observation group and 1519 ± 123 in the premature ventricular phase in the observation group (1932 ± 168) and (2872 ± 142), respectively Statistical significance (P <0.05). The incidence of adverse reactions in the observation group (12.5%) was significantly lower than that in the control group (30.0%) (P <0.05). Conclusion The application of simvastatin in patients with clinically arrhythmia can significantly improve the clinical effect, improve the clinical symptoms, and have higher safety, and have wide application value.