高血压患病率相当高。医疗实践证明,长期规律性的降压治疗对控制高血压、预防并降低高血压的并发症起着重要作用。为了减少患者的服药次数,并使能坚持服药,我们改进了降压药物的剂型,试制了长效复方可乐定降压片。这种片剂主要是通过剂型设计延缓药物的释放,并复合应用中枢降压药可乐定、血管扩张药双肼酞嗪及利尿降压药双氢氯噻嗪,以发挥 The prevalence of hypertension is quite high. Medical practice has proved that long-term regular antihypertensive treatment plays an important role in controlling hypertension, preventing and reducing the complications of hypertension. In order to reduce the number of patients taking medication, and to enable adherence to medication, we improved the dosage form of antihypertensive drugs and trial-produced a long-acting compound clonidine. This tablet is mainly designed to delay the release of drugs through the formulation design, and the combination of central antihypertensive drug clonidine, vasodilators double hydrazine phthalazine and diuretic hydrochlorothiazide antihypertensive drugs to play