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目的:观察消翳方配合西药常规治疗单纯疱疹病毒性角膜炎的疗效及对患者T细胞亚群的影响。方法:将100例单纯疱疹病毒性角膜炎患者随机分为两组各50例,治疗组口服消翳方并配合西药常规治疗;对照组口服无环鸟苷片。治疗前后分别测定T细胞亚群值。结果:治疗组T细胞亚群值治疗后较治疗前差异有统计学意义(P<0.05);对照组治疗后T细胞亚群值较治疗前虽有提高,但差异无统计学意义(P>0.01)。结论:消翳方能在抗病毒的同时使机体细胞免疫功能增强,对HSK的有效防治、防盲具有重要意义。
OBJECTIVE: To observe the curative effect of Xiaoyu Fang and western medicine on herpes simplex virus keratitis and its effect on T lymphocyte subsets. Methods: 100 cases of herpes simplex keratitis patients were randomly divided into two groups of 50 cases, the treatment group oral Xiaoya prescription and western medicine routine treatment; the control group oral acyclovir tablets. T cell subsets were measured before and after treatment. Results: The T cell subsets in the treatment group were significantly different from those before treatment (P <0.05). The T cell subsets in the control group were higher than those before treatment, but the difference was not statistically significant (P> 0.01). Conclusion: Xiao-Fang prescription can enhance the cellular immune function of antivirus while preventing and curing the HSK effectively.