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本文旨在评估尼卡地平(一种双氢吡啶钙通道阻滞剂)对治疗妊娠期高血压时对胎儿及孕妇的影响.共40例患有轻度或中度高血压的妊娠妇女口服尼卡地平(20mg/次,3次/d),平均治疗时间为9±2.l周),另外20例严重子痫前期的病人(舒张压>14.7kPa,24h尿蛋白>500mg)则按2,4,6mg/(kg·d)静脉应用尼卡地平治疗,平均用药时间5.3±3.6d.结果 口服尼卡地平组患者血压与治疗前相比,收缩压和舒张压均显著下降(P<0.01).20例静
This article aims to assess the effects of nicardipine, a calcium dihydropyridine calcium channel blocker, on the fetus and pregnant women for the treatment of gestational hypertension.A total of 40 pregnant women with mild or moderate hypertension received oral injections (20mg / time, 3 times / d), the average treatment time was 9 ± 2.l weeks), and the other 20 patients with severe preeclampsia (diastolic pressure> 14.7kPa, 24h urinary protein> 500mg) , 4,6mg / (kg · d) intravenous nicardipine treatment, the average medication time of 5.3 ± 3.6d.Results In patients with oral nicardipine, the systolic blood pressure and diastolic blood pressure were significantly lower than those before treatment (P < 0.01) .20 cases of static