论文部分内容阅读
目的探讨重型颅脑损伤并发急性肝功能损害的有关发生机制及其临床意义。方法对2002年6月～2006年6月我们收治的102例重型颅脑损伤并发急性肝功能损害患者的临床资料进行回顾性分析,对肝功能检验指标进行统计学分析。结果显效44例,有效38例,无效20例。谷丙转氨酶(ALT)、天冬氨酸转氨酶(AST)、谷氨酰转肽酶(GGT)与GCS分值之间均呈负相关(P<0.01)。存活组的ALT、AST、GGT水平与死亡组比较有显著性差异(P<0.01)。结论重型颅脑损伤常致肝功能损害,肝功能损害程度与脑外伤的轻重程度及预后密切相关,注意监测及保护肝功能有利于患者康复。
Objective To investigate the pathogenesis and clinical significance of severe craniocerebral injury complicated by acute hepatic dysfunction. Methods The clinical data of 102 patients with severe craniocerebral injury complicated with acute hepatic dysfunction admitted from June 2002 to June 2006 were analyzed retrospectively, and the indexes of liver function tests were statistically analyzed. The results were effective in 44 cases, effective in 38 cases, ineffective in 20 cases. There was a negative correlation between ALT, AST, GGT and GCS score (P <0.01). Survival group ALT, AST, GGT levels compared with the death group was significantly different (P <0.01). Conclusions Severe craniocerebral injury often leads to liver damage. The degree of liver damage is closely related to the severity and prognosis of traumatic brain injury. Attention should be paid to the monitoring and protection of liver function in favor of rehabilitation.