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目的 通过对增生性玻璃体视网膜病变 (PVR)膜的病理、免疫组化观察 ,探讨巨噬细胞与PVR形成间关系的研究途径。方法 利用免疫组化技术对玻璃体手术中获得的人眼PVR膜进行病理学研究。结果 PVR的基本病理形态是损伤修复过程。 70 %膜标本中检测出巨噬细胞。结论 应进一步用免疫组化、分子生物学、免疫电镜方法 ,研究巨噬细胞与PVR发病间的关系
OBJECTIVE: To investigate the pathological and immunohistochemical observation of proliferative vitreoretinopathy (PVR) and to explore the possible pathway of macrophage-PVR formation. Methods Immunohistochemistry was used to study the pathology of human PVR films obtained during vitrectomy. Results The basic pathology of PVR was injury repair process. Macrophages were detected in 70% of the membrane specimens. Conclusion The relationship between macrophages and PVR should be further studied by immunohistochemistry, molecular biology and immunoelectron microscopy