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目的观察布拉氏酵母菌散对儿童抗生素相关性腹泻(AAD)疗效。方法 AAD患儿随机分为治疗组(常规治疗+口服布拉氏酵母菌散)与对照组(仅常规治疗),各35例,观察比较两组患儿平均便次和腹泻持续时间变化情况。结果治疗组在治疗第3、5、7天平均便次较对照组显著减少,差异有统计学意义(P<0.05);平均腹泻持续时间明显短于对照组,差异有统计学意义(P<0.05);治疗组治愈32例(91.4%)高于对照组治愈18例(51.4%),差异有统计学意义(P<0.01)。结论口服布拉氏酵母菌散治疗儿童AAD效果显著,无明显不良反应,且该药口味好,服用方便,家长与患儿均容易接受。
Objective To observe the curative effect of antibiotic-associated diarrhea (AAD) in children with B. Methods AAD children were randomly divided into treatment group (conventional therapy + oral administration of oral pasteuria) and control group (conventional treatment only), 35 cases each. The changes of average defecation and diarrhea duration were compared between the two groups. Results The treatment group on the 3rd, 5th and 7th day, the average number of times was significantly reduced compared with the control group, the difference was statistically significant (P <0.05); the average duration of diarrhea was significantly shorter than the control group, the difference was statistically significant (P < 0.05). There were 32 cases (91.4%) cured in the treatment group and 18 cases (51.4%) cured in the control group, the difference was statistically significant (P <0.01). Conclusion Oral administration of oral Saccharomyces boulardi has a significant effect on children with AAD, no obvious adverse reactions, and the drug tastes good, easy to take, parents and children are easy to accept.