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目的探讨新疆喀什伽师县农村维吾尔族男性HPV感染的分布及亚型特点,为新疆维吾尔族妇女HPV干预及宫颈癌预防提供理论依据。方法采用凯普导流杂交芯片技术对新疆宫颈癌高发区新疆喀什伽师县克孜勒博依乡430例维吾尔族男性进行21种HPV亚型的检测。结果 (1)430例男性HPV阳性率为26.28%,HPV阳性的男性中HPV16是最常见的类型,与其他类型比较阳性率差异有统计学意义(P<0.05)。(2)HPV感染的类型主要为16、58、31型;多重感染者15例,占HPV感染者的13.27%(15/113),多重感染以HPV16型合并感染为主,占86.67%(13/15)。结论新疆喀什伽师县克孜勒博依乡维吾尔族男性HPV阳性率较高,HPV感染的类型以HPV16为主,维吾尔族男性在维吾尔族宫颈癌发生中可能起一定作用。
Objective To investigate the distribution and subtypes of HPV infection in rural Uighur males in Kashgar Prefecture in Xinjiang and to provide theoretical basis for preventing HPV infection and preventing cervical cancer in Uighur women in Xinjiang. Methods The HPV genotypes were detected in 430 Uygur men in Kizil Boyi Township, a high incidence area of cervical cancer in Xinjiang, using Kapu flow-through hybridization. Results (1) The positive rate of HPV in 430 men was 26.28%. HPV16 was the most common type in HPV-positive men and the difference was statistically significant compared with other types (P <0.05). (2) The types of HPV infection were mainly 16,58,31; 15 cases were multiple infection, accounting for 13.27% (15/113) of HPV infection, multiple infection was HPV16 infection, accounting for 86.67% (13 / 15). Conclusions The positive rate of HPV in Uighur men in Kizil Boyi Township, Kashi Jiashi County, Xinjiang Province is high. The HPV type is predominant in HPV16, and Uighur men may play a role in the occurrence of Uigur cervical cancer.