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对处于不同地区的大骨节病病区儿童,非病区儿童和1组服硒病区的儿童(7岁～13岁),一次性口服0.1%亚硒酸钠0.5ml(相当于150μg硒),进行了硒负荷试验。结果表明:硒负荷试验能够简便、敏感准确地反映机体硒状态;病区儿童存在着硒缺乏,表现在硒负荷后尿硒排泄少,排泄高峰后延;服硒盐病区儿童硒负荷结果和非病区儿童一致。本文还对硒负荷试验的特点、意义以及和血、尿硒的关系进行了讨论。
In children with Kashin-Beck disease in different areas, non-ward children and children with selenium in group 1 (7 years old to 13 years old), 0.5 ml of 0.1% sodium selenite (equivalent to 150 μg selenium) , Conducted a selenium load test. The results showed that selenium load test can reflect selenium status easily, sensitively and accurately. Selenium deficiency exists in children in ward, which shows less selenium excretion and excretion after selenium load. Non-ward children are consistent. The paper also discussed the characteristics of selenium load test, its significance and the relationship between blood and urine selenium.