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目的 分析比较福建人群中 7个表型群体染色体异常情况。 方法 采用染色体 G显带技术 ,对 7个表型群体的外周血淋巴细胞或骨髓细胞染色体进行研究。 结果 在 7个不同表型群体中染色体异常比率 (% )分别为 :慢粒组 91.0 0 ,急非淋组 46 .5 0 ,智力低下组 2 7.78,无精子组 2 4.2 7,女性矮小或原发闭经组 2 1.6 2 ,习惯性流产组 2 .0 5 ,生育先天缺陷儿组 0。 结论 染色体检查对白血病患者的诊断、疗效和预后估计具有较大意义。人群中染色体异常发生率较高 ,染色体检查在临床诊治中具有较大意义 ,应加强染色体检查并提高检测水平 ,如采取高分辨技术 ,以提高临床对该类疾病的正确诊断 ,提供积极的治疗方案
Objective To analyze and compare the chromosomal abnormalities of seven phenotypic groups in Fujian population. Methods Chromosome G banding technique was used to study the chromosomes of peripheral blood lymphocytes or bone marrow cells of seven phenotypic groups. Results The percentage of chromosome abnormalities (%) in the seven different phenotype groups were 91.0 in the CML group, 46.5 in the JF group, 2 7.78 in the IQ group, 4.2 7 in the azoospermia group, Amenorrhea group 2 1.6 2, habitual abortion group 2.05, birth defects in children group 0. Conclusion Chromosome examination of leukemia patients with diagnosis, efficacy and prognosis of great significance. Chromosome aberrations in the population a higher incidence of chromosomal examination in the clinical diagnosis and treatment has great significance, should enhance the chromosomal examination and improve the detection level, such as the use of high-resolution technology to improve the clinical diagnosis of such diseases, to provide a positive treatment Program