鼻咽癌(NPC)是头颈部最常见的恶性肿瘤。NPC恶性程度高,往往在疾病的早期就有临近组织浸润,其颅底骨侵犯发生率为12.5%～56%[1-2],甚至高达75.8%[3]。颅底骨侵犯的患者将划分为T3～T4期,增加放疗照射剂量或辅以化疗 Nasopharyngeal carcinoma (NPC) is the most common malignancy of the head and neck. NPC has a high degree of malignancy and often has adjacent tissue infiltration early in the disease. The incidence of skull base bone invasion ranges from 12.5% ​​to 56% [1-2] and even up to 75.8% [3]. Skull base invasion of patients will be divided into T3 ~ T4 period, increasing radiation dose or adjuvant chemotherapy