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目的探讨慢性肺心病合并低钠血症的病因、治疗特点及对临床疗效的影响。方法随机选取176例慢性肺心病急性发作期患者,按照入院时血钠结果分为血钠正常组和低钠组,两组均给予综合治疗,低钠组给予补钠,观察治疗1周后临床疗效,及出院转归情况。结果治疗1周后血钠正常组总有效率明显优于低钠组(P<0.05);出院时低钠组病死率明显高于血钠正常组(P<0.05)。结论慢性肺心病急性发作期患者临床疗效及病情转归与低血钠程度相关,血钠越低,临床疗效越差,病死率也越高。
Objective To investigate the etiopathogenisis of chronic pulmonary heart disease combined with hyponatremia, the characteristics of treatment and its effect on clinical efficacy. Methods A total of 176 patients with acute exacerbation of chronic pulmonary heart disease were randomly divided into normal sodium group and low sodium group according to the results of sodium intake on admission. The patients in both groups were given combined treatment and the sodium group received sodium supplementation. After 1 week of treatment, Efficacy, and discharge to the situation. Results After 1 week of treatment, the total effective rate in the normal sodium group was significantly better than that in the low sodium group (P <0.05). The mortality in the low sodium group was significantly higher than that in the normal sodium group (P <0.05) at discharge. Conclusion The clinical efficacy and the prognosis of patients with acute episode of chronic pulmonary heart disease are related to the degree of hyponatremia. The lower the serum sodium is, the poorer the clinical effect is, and the higher the mortality is.