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口服避孕药(OC)的避孕机理是通过下丘脑-垂体-卵巢轴抑制排卵。服药期间由于药物的副反应,如:呕吐、腹泻可能减少药物的吸收从而影响药物的疗效。有关新的避孕药,如:孕二烯酮的肠肝循环少是有临床证据。本研究目的在于通过重复服用活性炭创造一个干扰OC肠肝循环的环境,研究两种不同OC使用期间在中期重复使用活性炭对排卵的影响。
The contraceptive mechanism of oral contraceptives (OC) is to inhibit ovulation through the hypothalamic-pituitary-ovarian axis. Medication due to side effects of drugs, such as: vomiting, diarrhea may reduce the absorption of drugs and thus affect the efficacy of drugs. The new contraceptives, such as: gestodene small intestine and liver circulation is a small clinical evidence. The aim of this study was to investigate the effect of repeated use of activated carbon on ovulation during two different OC use periods by creating an environment that interferes with enterohepatic circulation through repeated ingestion of activated carbon.