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目的：：探讨不同剂量泮托拉唑在急性非静脉曲张上消化道出血患者治疗中的应用效果.方法：随机选取我院收治的62例急性非静脉曲张上消化道出血患者为研究对象，将其随机分成观察组与参照组各31例，两组分别采用不同剂量的泮托拉唑进行治疗，对比两组的应用效果.结果：观察组显效率明显高于参照组，总有效率与参照组总有效率差异不明显(P ＞0．05)；观察组平均止血天数、平均输血量均比参照组要少，再出血率明显比参照组要低(P ＞0．05)；两组不良反应发生率差异不明显(P ＞0．05).结论：根据患者的出血症状来合理选择泮托拉唑的使用剂量，有利于对症治疗.“,”Objective:To study the effects of different dose of pantoprazole in patients with acute non variceal upper digestive tract hemorrhage in the treatment Methods:62 cases of bleeding patients of acute non variceal upper gastrointestinal in our hospital were chosen as the research object,which were randomly divided into observation group and control group with 31 cases in each group,two groups were used different doses of pantoprazole treatment,the application effect of the two groups were compared.Results:The effective rate of observation group was significantly higher than that of the control group,the total effective rate was not significantly different (P >0.05);the average number of bleeding days in the observation group was less than that in the control group,and the bleeding rate was significant-ly lower than the reference group (P >0.05),and the adverse reactions of the two groups were not significantly different (P >0.05).Con-clusion:It is symptomatic treatment to choose pantoprazole symptoms to patients with bleeding according to the reasonable choice of the dose.