保乳手术联合术后化疗对早期乳腺癌患者近期预后影响研究

来源 :中国临床实用医学 | 被引量 : 0次 | 上传用户:cyuch
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目的:探讨保乳手术联合术后化疗对早期乳腺癌患者近期预后的影响。方法选择2009年1月至2013年12月运城市中心医院收治的早期乳腺癌患者89例作为研究对象,根据不同手术方式分为两组,观察组47例给予保乳手术联合术后化疗,对照组42例给予改良根治术联合术后化疗,比较两组患者的手术情况、乳房美容效果及术后生存率、复发率、远处转移率。结果观察组手术时间、住院时间均短于对照组,差异有统计学意义(P<0.05),术中出血量亦少于对照组,差异有统计学意义(P<0.05);观察组优良率为82.98%,显著高于对照组的61.90%,差异有统计学意义(P0.05)。结论保乳手术联合术后化疗、改良根治术联合术后化疗均是治疗早期乳腺癌的有效手段,但保乳手术对患者损伤较轻,且乳房美容效果优于改良根治术,值得临床重视。“,”Objective To investigate the effect of breast conserving surgery combined with postoperative chemotherapy on the prognosis of early breast cancer patients.Methods From January 2009 to December 2013,89 patients with early breast cancer treated as the research object,89 patients with early breast cancer were selected as the research object,according to different operation methods were divided into 2 groups,the observation group of 47 were gived the treatment of the breast conserving surgery combined with chemotherapy,the control group of 42 cases were gived the treatment of modified radical mastectomy combined with chemotherapy.The operation,breast beauty effect and survival rate, recurrence rate and distant metastasis rate were compared between the 2 groups.Results In the observation group the operative time,blood loss,hospitalization time were lower than the control group,the difference was statistically significant (P<0.05);the observation group,the excellent and good rate was 82.98%,which was significantly higher than control group 61.90%,the difference is statistically significant (P0.05).Conclusion Breast conserving surgery combined with postoperative chemotherapy and modified radical surgery combined with postoperative chemotherapy is effective in the treatment of early breast cancer,but Bao milk surgery on patients with injury lighter and breast cosmetic effect is better than that of the modified radical mastectomy,it is worthy of attention.
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