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胃肠道肿瘤化疗的耐药性一直是困扰临床医师的一个难题。常用的肿瘤多药耐药性逆转剂由于严重的临床毒副作用 ,很难在体内达到体外有效的浓度 ,因而很难在临床上得到应用。红霉素是大环内酯类抗生素 ,是当今应用最为广泛的抗菌药物。随着临床和药理的深入研究 ,其应用日益拓宽?
Chemotherapy resistance in gastrointestinal tumors has long been a challenge for clinicians. Commonly used multidrug resistance tumor reversal agents due to serious clinical side effects, it is difficult to achieve in vitro effective concentrations, it is difficult to be clinically used. Erythromycin is a macrolide antibiotic and is the most widely used antimicrobial drug today. With the clinical and pharmacological in-depth study, its application broadens?