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在许多动物种属,已证明前列腺素 F_(2α)(PGF_(2α)具有溶黄体作用。最近发现,对于人黄体的甾体生成,PGF_(2α)具有抗促性腺激素作用。据此推测,PGF_(2α)在人类的离体黄体极可能有溶黄体作用,因为要维持人黄体的正常机能必需有 LH 的支持。值得注意的是,PGF_(2α)的抗促性腺激素作用仅在黄体期中期(7～11天)的黄体有效,而对早期黄体(1～3天)则无效。实验证明,人黄体的前列腺素F_(2α)含量及产生以及人黄体的 PGF_(2α)受体含量,在黄体期不同阶段并无差异。然而,早期人黄体的内源性儿茶酚胺含量似乎低于中期黄体。作者
In many animal species, prostaglandin F 2α (PGF 2α) has been shown to have a corpus luteum effect.PGF 2α has been recently found to have anti-gonadotropin effects on human luteal steroidogenesis, PGF 2α is highly likely to have a corpus luteum in human corpus luteum due to the need for LH support in order to maintain the normal function of the human corpus luteum.It is noteworthy that the anti-gonadotrophic effect of PGF 2α is observed only in the luteal phase The mid-term (7 to 11 days) of the corpus luteum is effective, but the early luteal phase (1 to 3 days) is invalid. Experiments show that human lutein prostaglandin F 2alpha content and production and human luteal PGF 2alpha receptor content , There was no difference at different stages of the luteal phase, however, the early catecholamines appear to have lower endogenous catecholamines than the mid-term luteal phase.