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目的评价钬激光在泌尿系结石的临床应用和疗效，探讨手术操作技巧及并发症的预防。方法分别对122例输尿管结石患者行输尿管钬激光碎石术，56例肾结石患者行经皮肾镜钬激光碎石术。结果116例输尿管结石一期碎石成功，结石较小者，碎石后不留置双J管；结石较大者，碎石后留置双J管，4~6w后拔除。手术时间30~90min，平均40min，无输尿管穿孔发生。51例肾结石一期碎石成功，术后留置硅胶肾造瘘管，5~7d拔除，留置双J管于1~2月内拔除，手术时间60~170min，平均102min，术中估计出血量约40~140ml，平均65ml。结论钬激光具有安全、微创、疗效确切等优点，为泌尿系结石治疗提供了新的可靠手段，具有广阔的应用前景，值得在基层医院大力推广。“,”Objective To evaluate the clinical application and effect of the holmium laser on the urinary calculi.To discuss the skills in the operative procedure and the prevention of complications. Methods 122 cases of ureteral calculi underwent holmium laser lithotripsy of ureteral, 56 cases of kidney stones in patients with percutaneous nephrolithotomy holmium laser lithotripsy. Results 116 cases of the lithotripsy of the ureteral calculi are successful after one stage treatment, for smaller, there was not the indwelling double J tube;for larger one, indwelling double J tube, and it was taken out after 4~6 weeks . Operation time was 30 ~ 90 minutes, the average time of operation was 40 minutes, there was no ureteral perforation. 51 cases of the lithotripsy of the renal calculus are successful after one stage treatment, indwelling silicone nephrostomy tube after the surgery and it was taken out in 5~7days. The indwelling double J tube was taken out in 1~2 months. Operation time was 60 ~170 minutes, the average time of operation was 102 minutes, the amount of bleeding was about 40~140ml, and the average blood was 65 ml during the surgery. Conclusion With the advantages of safety、minimal invasion and certain curative effect,holmium laser provide a new clinical method and has made this tool a versatile muli-purpose instrument for use in the endoscopic treatment of a wide of calculi in urinary system. It is worth promoting at the grass-roots hospital.