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目的:探讨慢性阻塞性肺疾病肺动脉高压合并肺栓塞患者的临床特点,为其诊断及治疗提供依据。方法:回顾2012年06月~2013年10月慢性阻塞性肺疾病肺动脉高压合并肺栓塞患者43例,将其作为本研究的实验组,选择同时期慢性阻塞性肺疾病肺动脉高压患者41例,将其作为对照组,对两组患者的临床资料进行回顾性分析,总结慢性阻塞性肺疾病肺动脉高压合并肺栓塞患者的临床特点。结果:①比较两组的临床症状及生命体征,除下肢非对称性肿胀外(实验组为44.2%,对照组为7.5%),其余观察指标均无统计学意义(P>0.05);②比较两组辅助检查结果,实验组的PaO2为(60.78±19.23)mm Hg、肺动脉高压为(30.77±10.23)mm Hg、D-二聚体为(2496.78±337.68)μg/L,对照组对应为(56.29±17.38)mm Hg、(10.23±4.18)mm Hg、(287.72±68.29)μg/L,两组差异均具有统计学意义(P<0.05)。结论:阻塞性肺疾病肺动脉高压合并肺栓塞患者具有下肢非对称性肿胀,PaO2、肺动脉高压及D-二聚体偏高的临床特点,诊断时应给予重视。
Objective: To investigate the clinical characteristics of patients with pulmonary hypertension complicated by pulmonary embolism in patients with chronic obstructive pulmonary disease (COPD) and provide the basis for its diagnosis and treatment. Methods: From June 2012 to October 2013, 43 patients with pulmonary hypertension complicated by pulmonary embolism in chronic obstructive pulmonary disease (COPD) were retrospectively reviewed. As the experimental group, 41 patients with pulmonary hypertension with chronic obstructive pulmonary disease As a control group, the clinical data of two groups were retrospectively analyzed, and the clinical features of patients with pulmonary hypertension complicated with pulmonary embolism in patients with chronic obstructive pulmonary disease were summarized. Results (1) The clinical symptoms and vital signs were compared between the two groups except for asymmetric swelling of the lower limbs (44.2% in the experimental group and 7.5% in the control group), and the rest of the observation indexes were not statistically significant (P> 0.05) In the two groups, the PaO2 was (60.78 ± 19.23) mm Hg, the pulmonary hypertension was (30.77 ± 10.23) mm Hg and the D-dimer was (2496.78 ± 337.68) μg / L in the experimental group and the control group was ( 56.29 ± 17.38) mmHg, (10.23 ± 4.18) mmHg, (287.72 ± 68.29) μg / L, respectively. There was significant difference between the two groups (P <0.05). Conclusion: Patients with pulmonary hypertension and pulmonary embolism have obstructive pulmonary disease with lower extremity asymmetry swelling, PaO2, pulmonary hypertension and D-dimer high clinical features, diagnosis should be given attention.