现已认识到支气管肺发育不良(BPO)占肺透明膜病需要机械通气的婴儿11～21%。尽管发病率如此高,很少有人了解它对正在发育的神经系统的影响。Northy第一个提出可能有BPD的神经学后遗症。他曾报道在BPD的幸存者中34%发生明显的神经学缺陷,如大脑瘫痪、智力落后、失明和耳聋。此后的研究经进一步证实,非进行性的神经学缺陷在所有低出生体重组中更常见于BPD婴儿。据报道发病率在25～90%。作者复习了在1983～1984年连续12个月期间所有圣·路易儿童医院新生儿监护中心的记录。37个婴儿确定为BPD。根据神经学检查结果可分为4个类型:(1)5个病儿有明显进行性的神经学疾病;(2)9个病儿有非进行性的神经学疾病;(3)19个病儿有正 It has been recognized that bronchopulmonary dysplasia (BPO) accounts for 11-21% of infants who require mechanical ventilation for hyaline membrane disease. Although the incidence is so high, few people understand its impact on the developing nervous system. Northy first proposed neurological sequelae that may have BPD. He reported 34% of the BPD survivors had significant neurological deficits such as cerebral palsy, mental retardation, blindness and deafness. Subsequent studies have further demonstrated that non-progressive neurological deficits are more common in BPD infants in all low birth weight groups. The incidence is reported at 25-90%. The author reviewed the records of all newborn care centers at St. Louis Children’s Hospital for the 12 consecutive months from 1983 to 1984. 37 infants identified as BPD. According to the results of neurological examination can be divided into four types: (1) 5 children with significant progressive neurological disease; (2) 9 children with non-progressive neurological disease; (3) 19 Children have positive