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因丝裂霉素具有减少肉芽组织增生的作用,故既往多应用于动物或人的声门下狭窄治疗,以减少术后扩张的次数。鉴于此Holland等人将其应用于后鼻孔狭窄的治疗中。为了评估术中应用丝裂霉素在改进后鼻孔狭窄患儿术后软组织再狭窄的发生中的作用,该作者对原发性后鼻孔狭窄接受手术的患者行回顾性研究,其中8例年龄从14天至12岁患者术中局部应用
Because mitomycin has the effect of reducing the proliferation of granulation tissue, it is often used in animal or human subglottic stenosis treatment to reduce the number of postoperative expansion. In view of this Holland et al. It is applied to the treatment of posterior nostril stenosis. In order to evaluate the role of intraoperative use of mitomycin in the treatment of postoperative soft tissue restenosis in children with improved nasal stenosis, the authors performed a retrospective study of patients undergoing primary retroperitoneal stenosis undergoing surgery, of whom 8 14 days to 12 years of age in patients with local application