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弥漫性痘疮样胃炎是胃粘膜炎症的少见类型。炎症主要累及胃底和胃体,包括粘膜皱襞粗大,充血和水肿,在隆起粘膜上见有散在糜烂。临床表现为上腹部疼痛,部分患者类似消化性溃疡疼痛以及厌食、恶心,偶有呕吐、体重减轻、隐性或显性出血引起的贫血、低蛋白血症引起的浮肿等,部分病例在服抗炎药后发病。一般用X线双重对比造影和内窥镜检查可作出诊断。基础的和刺激的胃酸分泌和空腹血清胃泌素浓度均可在正常范围内。组织学特征为胃粘膜浅表溃疡、固有膜内有慢性炎症浸润、胃腺体肿大而没有特异细胞丢失,这些均有别于Ménétrier病、肥厚性高分泌性胃病和嗜酸性胃炎。
Diffuse varicella gastritis is a rare type of gastric mucosal inflammation. Inflammation mainly involves the fundus and corpus, including mucosal folds thick, congestion and edema, see in the uplift of the mucosa scattered erosion. Clinical manifestations of upper abdominal pain, some patients with pain similar to peptic ulcer and anorexia, nausea, occasional vomiting, weight loss, anemia caused by recessive or dominant bleeding, hypoalbuminemia caused by edema, and some cases in the service Inflammation after the onset. General double contrast with X-ray contrast and endoscopy can make a diagnosis. Both basal and stimulated gastric acid secretion and fasting serum gastrin concentrations may be within normal limits. Histological features of gastric mucosal superficial ulcers, chronic inflammatory infiltration within the intrinsic membrane, gastric gland enlargement without specific cell loss, these are different from the Ménétrier disease, hypertrophic gastropathy and eosinophilic gastritis.