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随着超广谱β-内酰胺酶类抗生素在临床上广泛使用,抗生素的选择压力日益增加,产超广谱β-内酰胺酶(extended-spectrumβ-lacta2mases,ESBLs)细菌的感染已呈世界性流行。产ESBLs细菌的出现给临床抗感染治疗带来众多问题:死亡率增高、住院时间延长、治疗经费上升、医生的治疗选择
With the extensive use of extended-spectrum β-lactamase antibiotics in clinics, the pressure of antibiotic selection is increasing day by day. Infection with extended-spectrum β-lactamases (ESBLs) bacteria has become worldwide popular. The emergence of ESBLs-producing bacteria poses numerous problems for clinical anti-infective treatment: increased mortality, prolonged hospital stays, increased funding for treatment, and physician’s treatment options