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目的分叶状毛细血管瘤的临床病理特点。方法采用HE染色及免疫组化技术对37例分叶状毛细血管瘤进行观察。结果肿瘤呈单发息肉状,直径多<2cm,肿瘤位于黏膜或真皮内,由增生的毛细血管瘤形成分叶结构,部分表面有溃疡形成或出血。免疫组化:血管内皮细胞FVIII、CD31、CD34、表达(+)。结论分叶状毛细血管瘤主要发生在成人,可自愈,部分复发,需与包括血管内皮瘤、血管肉瘤在内的多种血管病变鉴别。
Purpose of lobular capillary hemangioma clinical and pathological features. Methods 37 cases of lobulated capillary hemangioma were observed by HE staining and immunohistochemistry. Results The tumor was single polypoid, more than 2cm in diameter. The tumor was located in the mucosa or dermis. The tumor formed lobular structure by hyperplasia of capillary hemangioma, and some of the surface had ulceration or bleeding. Immunohistochemistry: Vascular endothelial cells FVIII, CD31, CD34, expression (+). Conclusions The lobulated capillary hemangioma mainly occurs in adults, which can heal and partially recurrent. It needs to be differentiated from other vascular diseases including hemangioendothelioma and angiosarcoma.