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以往评价抗生素药效学的指标主要为最低抑菌浓度、最低杀菌浓度、时间杀菌曲线法。抗生素的后效应(Postantibiotic Effects,PAE)这一理论的提出,为抗生素药效学的研究及设计合理的给药方案又提供了新的重要参数和依据。铜绿假单胞菌是院内感染的主要病原菌之一,引起的感染多为继发感染
The past evaluation of antibiotic pharmacodynamics indicators are the minimum inhibitory concentration, minimum bactericidal concentration, time sterilization curve method. The introduction of the theory of postantibiotic effects (PAE) provides new important parameters and basis for the study of antibiotic pharmacodynamics and the design of rational drug delivery schemes. Pseudomonas aeruginosa is one of the main pathogenic bacteria in nosocomial infections, causing infections mostly secondary infection