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狄戈辛血药浓度的测定通常采用放射免疫测定法。其它药物及病人的生化异常可能对测定结果有干扰,另外应注意非蛋白性样品必须加入血清以减少因抗体与药物结合而引起的误差,还有病人同时使用螺旋内酯则能引入0～1ng/ml狄戈辛的正误差。现在已经确定狄戈辛的血清浓度与其疗效、毒性表现密切有关。病人的稳态血清浓度在0.7～1.5ng/ml时大部分病人获得满意
The determination of blood plasma concentration of dicoxib usually uses radioimmunoassay. Other drugs and patient biochemical abnormalities may interfere with the determination results, in addition should pay attention to non-protein samples must be added to serum to reduce the antibody and drug combination caused by the error, while patients with spiral lactone can introduce 0 ~ 1ng / ml DIOSXIN positive error. It has now been determined that Dioxin’s serum concentration is closely related to its efficacy and toxicity. Patients with steady-state serum concentrations of 0.7 ~ 1.5ng / ml most patients satisfied