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目的探讨女性生殖道假丝酵母菌感染状况及防治方法。方法采集阴道清洁度异常分泌物标本进行假丝酵母菌分离鉴定,再用MIC法进行药敏试验。结果610例分泌物检出假丝酵母菌405株占66.39%(405/610),其中白色假丝酵母菌317株占78.27%,热带假丝酵母菌31株占7.65%,光滑假丝酵母菌26株占6.42%,克氏假丝酵母菌18株占4.44%,其他假丝酵母菌13株占3.21%;阴道清洁度Ⅲ、Ⅳ级假丝酵母菌检出率分别为44.69%、55.3%(χ2=9.13、P<0.005);假丝酵母菌对7种抗菌药物敏感率在42.31%～100.00%,其中以AMB抗菌活性最高。结论清洁度异常分泌物假丝酵母菌检出率高,自身感染和不洁性行为是传播主要途径。
Objective To investigate the female reproductive tract Candida infection and prevention and treatment methods. Methods Samples of vaginal candidiasis secreted by vaginal candidiasis were isolated and identified, and then susceptibility testing was conducted by MIC method. Results Among the 610 cases, 405 strains of Candida were detected, accounting for 66.39% (405/610), of which 317 strains accounted for 78.27% of Candida albicans, 31 strains of Candida tropicalis accounted for 7.65%, Candida glabrata 26 strains accounted for 6.42%, Candida kawachi 18 strains accounted for 4.44%, other Candida 13 strains accounted for 3.21%; vaginal cleanliness Ⅲ, Ⅳ grade Candida albicans detection rates were 44.69%, 55.3% (χ2 = 9.13, P <0.005). The susceptibilities of Candida to the seven antibacterials ranged from 42.31% to 100.00%, of which AMB had the highest antibacterial activity. Conclusion The detection rate of Candida albicans, which is an abnormal cleanliness, is the main route of transmission.