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目的探讨双嘧达莫(潘生丁)、甲氰咪胍联用治疗小儿病毒性腹泻的临床疗效及安全性。方法 120例病毒性腹泻患儿随机分成观察组和对照组,各60例。对照组采取常规治疗,观察组采取潘生丁联合甲氰咪胍治疗,比较两组临床疗效及安全性。结果观察组与对照组均无不良反应发生。观察组总有效率93.33%,对照组总有效率76.67%,观察组总有效率明显高于对照组,差异有统计学意义(P<0.05);观察组止泻时间、疗程时间均短于对照组,差异有统计学意义(P<0.05)。结论潘生丁联合甲氰咪胍治疗小儿病毒性腹泻的临床疗效显著,止泻时间及治疗时间较短,无不良反应,是一种安全有效的治疗方法。
Objective To investigate the clinical efficacy and safety of dipyridamole combined with cimetidine in the treatment of viral diarrhea in children. Methods 120 cases of viral diarrhea children were randomly divided into observation group and control group, 60 cases each. The control group to take conventional treatment, observation group taking dipyridamole combined with cimetidine treatment, the clinical efficacy and safety of the two groups were compared. Results There was no adverse reaction between the observation group and the control group. The total effective rate was 93.33% in the observation group and 76.67% in the control group. The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). The diarrhea time and treatment duration in the observation group were shorter than those in the control group Group, the difference was statistically significant (P <0.05). Conclusion The clinical efficacy of dipyridamole and cimetidine in the treatment of viral diarrhea in children is significant, and its antidiarrheal time and treatment time are short with no adverse reactions. It is a safe and effective treatment.