This paper investigates QR matrix decomposition based successive interference cancellation multiuser detection algorithms in synchronous uplink for code division multiple access based multiple input multiple output orthogonal frequency division multiplexing system. The Symbol Error Rate(SER) performance of the optimal order and the suboptimal order QR-SIC MUD algorithms are compared with conventional zero forcing and minimum mean square error multiuser detection algorithms by Monte Carlo simulations. Complexity analysis is presented at the end of the paper. Both our simulation results and complexity analysis show that SER performance of QR-Successive Interference Cancellation (QR-SIC) algorithms is superior to those of zero forcing(ZF) and minimum mean square error algorithms, and the suboptimal order QR-SIC algorithm has a good trade-off between SER performance and computation complexity.