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测定新生儿败血症时血清的１２种急性期蛋白成分，结果表明，败血症新生儿血清α１ＡＴ含量比正常新生儿明显增高，α１ＡＧ、ＨＰ、ＣＰ、Ｃ１ｑ、Ｃ４、Ｃ５、Ｃ９、Ｂｆ含量均极显著高于正常新生儿，而α２Ｍ含量比正常新生儿明显降低，Ｔｆ含量极显著低于正常新生儿，Ｃ３含量无显著变化。说明新生儿在受到细菌感染及其毒素刺激时，同样能有年长儿以至成人的抗感染急性期反应。文中对急性期蛋白变化的生理病理意义及其在机体抗感染免疫调节网络中的作用进行了分析。
The results showed that serum α1AT levels in neonates with sepsis were significantly higher than those in normal neonates, and the contents of α1AG, HP, CP, C1q, C4, C5, C9 and Bf were extremely high In normal newborns, α2M levels were significantly lower than normal neonates, Tf content was significantly lower than normal newborns, C3 content showed no significant change. Description of newborns in bacterial infection and toxins stimulated, the same can have children and adults anti-infection acute phase response. The physiological and pathological significance of the protein changes in acute phase and its role in the anti-infective immune regulation network of the body were analyzed.