前言 通用航空飞行员在12500 ft(3810m)的高空持续飞行不用补充氧气。然而,在12500 ft(3810m)的高度以下缺氧的情况是可能发生的。在低高度下执行简单和复杂任务的实验室研究表明,受试个体的飞行员耐受能力和操作技能具有较高的可变性。本研究对通用航空飞行员的生理反应、模拟飞行操作表现和对轻度缺氧的主观报告作出了评估。方法 将轻度缺氧组的10名飞行员和正常供氧对照组的10名飞行员进行比较。在为期3天,每天2h的跨国飞行方案中, Foreword General Aviation pilots continue their flight at 12500 ft (3810 m) without oxygen. However, hypoxia can occur below 12500 ft (3810 m). Laboratory studies that performed simple and complex tasks at low altitudes showed that pilots tolerance and maneuverability of the individual under test were highly variable. This study assessed the physiological responses of general aviation pilots, simulated flight performance and subjective reports of mild hypoxia. Methods Ten pilots in the mild hypoxia group and 10 pilots in the normal oxygenation control group were compared. In a three-day, 2h daily transnational flight program,