恶性肿瘤的无限制侵袭性生长及其转移依赖于血管生成。肿瘤血管生成是一个复杂的多步骤的过程 ,多种生长因子参与 ,血管内皮生长因子 (VEGF)是最重要的血管生长因子 ,与肿瘤的预后有关。本文旨在对VEGF家族及其在肿瘤血管生成、眼球内肿瘤中的作用作一综述 Invasive growth and metastasis of malignant tumors depend on angiogenesis. Tumor angiogenesis is a complex and multi-step process involving multiple growth factors. Vascular endothelial growth factor (VEGF) is the most important vascular growth factor, which is related to the prognosis of the tumor. This article aims to review the role of the VEGF family and its role in tumor angiogenesis and intraocular tumors