论文部分内容阅读
苯二氮(艹卓)类(Benzodiazepines)药是自五十年代后期发展的一类抗焦虑和镇静催眠药。其中利眠宁(Librium)首先用于临床,治疗焦虑不安的精神紧张等。进一步研究发现分子中氮上的氧和脒的结构都不是生理活性的必要成分,于是又合成了同类型药物安定(Diazepam,Valium)经临床应用证明,作用较利眠宁强,除治疗神经官能症外,是控制癫痫持续状态的较好药物。后又研制出硝基安定(Nitrazepam)、去甲
Benzodiazepines are a class of anti-anxiety and sedative-hypnotic drugs that have developed since the late 1950s. Librium (Librium) first used in clinical treatment of anxiety and anxiety and so on. Further study found that nitrogen and oxygen in the molecule and amidine structure are not essential components of physiological activity, so they synthesized the same type of drug Diazepam (Valium) proved by clinical application, the effect is better than Chronic, rather than the treatment of nerve function Disease, is to control the status of epilepsy better drug. Nitrazepam was subsequently developed and de-nailed