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目的 :了解自然状态下风疹的流行情况 ,为风疹疫苗纳入计划免疫管理提供依据。方法 :采用半对数回归 EL ISA法对健康人群的风疹抗体水平进行检测。结果 :本次调查正常人群抗体阳性率为 70 .1%,GMT为 1∶ 6 5 .5 1,其中≥ 15岁女性抗体阳性率为 78.6 %,GMT为 1∶ 5 5 .5 1。地区间人群抗体阳性率无显著性差异 ,年龄组间 <1岁组儿童抗体水平较高。结论 :盐城市风疹自然流行率较高 ,风疹疫苗初免年龄应在 1岁以上 ,控制风疹流行的策略应该是重点保护 15岁以下儿童及育龄期妇女。
OBJECTIVE: To understand the prevalence of rubella in natural conditions and provide evidence for the inclusion of rubella vaccine in planned immunization management. Methods: The semi-logarithmic regression ELISA method was used to detect rubella antibody levels in healthy subjects. Results: In this survey, the positive rate of antibody in normal population was 70.1% and the GMT was 1:65.51, of which the positive rate of female antibody ≥15 years old was 78.6% and the GMT was 1:55.51. There was no significant difference in the antibody positive rate among the population in different regions. The level of antibody in children <1 year old was higher than that in other age groups. Conclusion: The natural prevalence of rubella in Yancheng City is relatively high. The age of first immunization of rubella vaccine should be above 1 year old. The strategy of controlling the prevalence of rubella should focus on protection of children under 15 and women of childbearing age.