AIM:To retrospectively evaluate the computed tomography(CT)/magnetic resonance imaging(MRI) imaging features of epithelioid angiomyolipoma of the liver(Epi-HAML),with pathology as a reference. METHODS:The CT/MRI findings(number,diameter, lobar location,and appearance of lesions)in a series of 10 patients with 12 pathologically proven epithelioid angiomyolipomas of the liver were retrospectively analyzed.The imaging features,including attenuation/ signal intensity characteristics,presence of fat, hypervascular,outer rim,and vessels within lesion, were evaluated and compared with that of non-Epi-HAML in 11 patients(13 lesions).The Fisher exact test was used to compare difference in probability of imaging features between the two types. RESULTS:For 21 patients,CT images of 15 patients and MR images of six patients were available.No patient underwent two examinations.For the 15 patients with a CT scan,all HAML lesions in the two groups(10 Epi-HAML and seven non-Epi-HAML) manifested as hypoattenuation.For the six patients with MRI,all lesions(two Epi-HAML and six non-Epi- HAML)were hypointense on T1WI(fat suppression)and hyperintense on T2WI.There were 10 non-Epi-HAML, but only two Epi-HAML lesions showed the presence offat,which significantly different between the two types (P=0.005).On the dynamic contrast enhancement (DCE)imaging,eight Epi-HAML,and 13 non-Epi lesions manifested as hypervascular.Punctate or curved vessels were displayed in 10 Epi-HAML as well as in nine non-Epi lesions and outer rim enhancement could be found with eight Epi-HAML as well as six non-Epi lesions. CONCLUSION:Little or no presence of adipose tissue was found to be an imaging feature of Epi-HAML,compared with the non-Epi type.In addition, hypervascularity with opacification of central punctiform or filiform vessels on DCE would be a characteristic enhancement pattern for Epi-HAML. AIM: To retrospectively evaluate the computed tomography (CT) / magnetic resonance imaging (MRI) imaging features of epithelioid angiomyolipoma of the liver (Epi-HAML), with pathology as a reference. METHODS: The CT / MRI findings lobar location, and appearance of lesions) in a series of 10 patients with 12 pathologically proven epithelioid angiomyolipomas of the liver were retrospectively analyzed. imaging features, including attenuation / signal intensity characteristics, presence of fat, hypervascular, outer rim, and vessels within lesion, were evaluated and compared with that of non-Epi-HAML in 11 patients (13 lesions). The Fisher exact test was used to compare difference in probability of imaging features between the two types. RESULTS: For 21 patients, CT images of 15 patients and MR images of six patients were available. No patient underwent two examinations. For the 15 patients with a CT scan, all HAML lesions in the two groups (10 Epi-HAML and seven non-Epi-HAML) manifested as hypo attenuation. For the six patients with MRI, all lesions (two Epi-HAML and six non-Epi-HAML) were hypointense on T1WI (fat suppression) and hyperintense on T2WI.There were 10 non-Epi-HAML, but only two Epi - HAML lesions showed the presence offat, which significantly differs between the two types (P = 0.005). On the dynamic contrast enhancement (DCE) imaging, eight Epi-HAML, and 13 non-Epi lesions manifested as hypervascular. were displayed in 10 Epi-HAML as well as in nine non-Epi lesions and outer rim enhancement could be found with eight Epi-HAML as well as six non-Epi lesions. CONCLUSION: Little or no presence of adipose tissue was found to be an imaging feature of Epi-HAML, compared with the non-Epi type. In addition, hypervascularity with opacification of central punctiform or filiform vessels on DCE would be a characteristic enhancement pattern for Epi-HAML.