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估算AUC和AUMC的最佳数值积分法以一组浓度-时间测定值计算曲线下面积(AUC)及矩曲线下面积(AUMC)的方法在非房室药动学研究中起着重要作用,这些量可由实验数据估算。先将实验数据拟合,以房室模型为基础的函数C(t),然后对C(t)和t·C(t)...
Estimating the best numerical integration of AUC and AUMC The method of calculating the area under the curve (AUC) and the area under the curve (AUMC) with a set of concentration-time measurements plays an important role in the study of non-atrial pharmacokinetics, and these The amount can be estimated from the experimental data. The experimental data are first fitted to the chamber model based function C (t), then to C (t) and t · C (t) ...