在研究职业性致敏物质时,常因某化学物可引起接触性致敏而认为此化学物尚可引起呼吸道致敏,反之亦然,遂统称为致敏物,实则二者应予区别。本室在研究异佛尔酮二异氰酸酯(IPDI)是否为致敏物时,一时难以断定,原因是IPDI可引起家兔耳肿,自愿者皮肤斑贴试验阳性;流行病学调查显示接触者皮肤过敏 In the study of occupational sensitizing substances, often because of a chemical sensitization can cause contact sensitization that the chemical can still cause respiratory sensitization, and vice versa, then collectively referred to as allergens, but the two should be distinguished. The room in the study isophorone diisocyanate (IPDI) is a sensitizer, the temporary difficult to determine, because IPDI can cause ear swelling in rabbits, volunteers skin patch test positive; epidemiological survey showed that contact with the skin allergy