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单纯疱疹性角膜炎(以下简称单疱性角膜炎)为常见眼病,病情迁延反复发作,又无特效药物治疗,成为目前致盲率较高眼病之一。现国内外一致认为机体细胞免疫机能低下与该病的发病有关。自1982年1月至1985年1月,对我科门诊观察治疗的165例单疱性角膜炎患者中的50例随机的作了细胞免疫(E-玫瑰花结合率和淋巴细胞转化率)测定,并以此为原始材料,对其中25例细胞免疫机能显著低下的患者应用免疫增强剂(左旋咪唑或转移因子)治疗,达临床治愈或基本治愈后再进行细胞免疫复测,以作动态观察,为克服临床观察的片面性,着重将实验室资料汇集分析,现报告如下:
Herpes simplex keratitis (hereinafter referred to as unilateral keratitis) is a common eye disease, recurrent episode of prolonged illness, and no effective drug treatment, has become one of the current high blinding eye disease. At home and abroad are now agreed that the body’s cellular immune function is low and the incidence of the disease. From January 1982 to January 1985, 50 out of 165 patients with unicellular keratitis treated in our outpatient department were randomized to receive cellular immunization (E-rose incorporation and lymphocyte conversion) , And using this as raw material, immunostimulants (levamisole or transfer factor) were applied to 25 patients whose cellular immunity was significantly lower than that of the control group. After clinical cure or basic cure, cellular immune retest was performed for dynamic observation , In order to overcome the one-sided clinical observation, focusing on the collection of laboratory data analysis, are as follows: