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Langerhan细胞(LC)是一种广泛分布于机体表面,存在于眼部结膜及角膜缘,而角膜中央则缺如,但在某些因素下LC可向角膜中央迁移,在免疫及非免疫性反应中均起重要作用的细胞。作者通过在豚鼠角膜中央置缝线动态观察眼表LC的变化,对非免疫性因素致LC的增殖与移行进行研究,以探讨损伤和异物刺激下LC的活动和作用。结果置缝线2d后角膜缘处LC增多,角膜中央开始发现LC,8d后角膜中央部增多,
Langerhan’s cells (LCs) are widely distributed on the surface of the body and exist in the conjunctiva and limbus of the eye, while the cornea is absent at the center. However, LC can migrate towards the cornea under certain conditions. In the immune and non-immune reactions In the play an important role in the cell. By observing the LC changes in the central cornea of guinea pig, the authors studied the LC proliferation and migration induced by non-immune factors in order to explore the action and role of LC in injury and foreign body stimulation. Results Suture 2d after the limbal LC increased, began to find the central corneal LC, central corneal increased after 8d,