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Abbott MS-2/LAL系统测定是根据鲎变形细胞溶出物(Limulus Amebocyte Lysate,LAL)可与试样中的内毒素反应生成一种可见的、不溶性的絮状网状凝胶,这种网状物较脆,反应混合物十分粘稠。作者利用MS-2振摇装置进行分散,然后用多功能分光光度计进行测定。MS-2系统可供自动LAL测试,以筛选各种注射药物。于35°,每一组件可同时培育88只样品,每隔一分钟于670 nm处测量每一反应混合物的光密度,然后确定标准内毒素-LAL的反应动力学。再观察各注射
The Abbott MS-2 / LAL System is based on the detection of Limulus Amebocyte Lysate (LAL) that reacts with endotoxin in the sample to form a visible, insoluble, flocculent reticular gel. This reticular The material is brittle and the reaction mixture is very viscous. The authors used a MS-2 shaker to disperse and then measured with a multi-function spectrophotometer. The MS-2 system provides automated LAL testing to screen a wide range of injectables. At 35 [deg.], 88 samples can be incubated simultaneously in each module, the optical density of each reaction mixture is measured at 670 nm every minute, and the reaction kinetics of the standard endotoxin-LAL is then determined. Then observe each injection