卷胚属植物提取物的制备及其保肝作用

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卷胚属植物Cochiospermum planchonii根提取物的制备方法是将干燥,粉碎的根用蒸馏水在56~64℃,100kPa压力下提取25min以上,该提取物用作保肝药。这种植物的干燥粉碎根(500g)和水(10L)常压下加热至60℃,0.5h,过滤,不溶物再提取两次与水溶部分(30L,pH5)合并,45℃减压浓缩至5L.浓缩液冷冻干燥。提取物含多酚,UV最大吸收波长为210nm和265nm,它不含生物碱和皂甙。初步研究表明含有没食子酸及其衍生物,特别是其糖甙和酯。该提取物对扑热息痛引起小鼠肝损伤的保护作用优于N-乙酰半胱氨酸。服用该提取物可挽救因暴发性肝 The root preparation of the Cochiospermum planchonii root extract of the genus Reticulum was extracted from the dried, crushed roots using distilled water at 56-64° C. under a pressure of 100 kPa for more than 25 minutes. This extract was used as a hepatoprotective agent. The dry and crushed roots (500 g) and water (10 L) of this plant were heated to 60° C. for 0.5 h under normal pressure and filtered. The insolubles were extracted twice and combined with the water-soluble portion (30 L, pH 5) and concentrated under reduced pressure at 45° C. 5L. The concentrate was freeze-dried. The extract contains polyphenols with UV absorption wavelengths of 210 nm and 265 nm, which are free of alkaloids and saponins. Preliminary studies showed gallic acid and its derivatives, especially its glycosides and esters. The extract was superior to N-acetylcysteine ​​in protecting against liver injury in mice caused by paracetamol. Taking this extract can save fulminant liver
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