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对153例恶性血液病(HM)医院感染(NI)回顾性调查表明HM的医院感染率(NIR)52.9%。NIR粒细胞缺乏组(粒缺组)87.2%,非粒细胞缺乏组(非粒缺组)41.2%(P<0.005);因NI死亡人数粒缺组6例,非粒缺组1例(P<0.005);NI患者人均感染粒缺组19.2d,比非粒缺组多10d(P<0.001)。急性白血病(AL)与淋巴瘤的NIR经x2检验P>0.05,HM患者肝炎病毒携带与否其NIR差异无统计学检验显著意义。粒细胞缺乏是HM患者发生NI主要危险因素,提高功能完善的粒细胞数是防治HM的NI关键之一。
A retrospective survey of 153 hospitalized patients with hematologic malignancies (HM) showed a 52.9% nomenclature for HM in hospital. In NIR group, 87.2% in non-granulocyte group and 41.2% in non-granulocyte group (P <0.005) 1 patient in the absence group (P <0.005). NI patients were 19.2 days longer than the non-deficient group (P <0.001). NIR of acute leukemia (AL) and lymphoma was x2 test (P> 0.05). There was no significant difference in NIR between patients with HM and with or without hepatitis B virus infection. The lack of agranulocytosis is a major risk factor for NI in patients with HM, and improving the number of fully functional granulocytes is one of the key factors in the prevention and treatment of HM.