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自16世纪人们发现流感以来,在世界范围内流感每年都会夺去几十万人的生命。疫苗是预防和控制流感病毒感染的最重要手段。传统的流感疫苗针对同一亚型流感病毒的保护效果较好,但不能有效地预防不同亚型流感病毒的感染。近年来研究人员试图研发能同时预防多种流感病毒亚型感染的流感通用疫苗。基于甲型流感病毒血凝素茎部区的流感通用疫苗是近年来流感疫苗研究的一个热点,本文将简要介绍有关这方面的研究进展。
Since the 16th century when people discovered the flu, the flu has claimed hundreds of thousands of lives every year in the world. Vaccines are the most important means of preventing and controlling influenza virus infections. Traditional influenza vaccines against the same subtype of influenza virus protective effect is better, but can not effectively prevent the different subtypes of influenza virus infection. In recent years, researchers have tried to develop a universal flu vaccine that can simultaneously prevent the infection of many influenza virus subtypes. The universal influenza vaccine based on the hemagglutinin stem area of influenza A virus is a hot spot in the research of influenza vaccine in recent years. This article will briefly introduce the research progress in this area.